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Mendelian disorders of PI metabolizing enzymes.
Staiano L, De Leo MG, Persico M, De Matteis MA. Staiano L, et al. Among authors: de leo mg. Biochim Biophys Acta. 2015 Jun;1851(6):867-81. doi: 10.1016/j.bbalip.2014.12.001. Epub 2014 Dec 12. Biochim Biophys Acta. 2015. PMID: 25510381 Review.
Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL.
De Leo MG, Staiano L, Vicinanza M, Luciani A, Carissimo A, Mutarelli M, Di Campli A, Polishchuk E, Di Tullio G, Morra V, Levtchenko E, Oltrabella F, Starborg T, Santoro M, Di Bernardo D, Devuyst O, Lowe M, Medina DL, Ballabio A, De Matteis MA. De Leo MG, et al. Nat Cell Biol. 2016 Aug;18(8):839-850. doi: 10.1038/ncb3386. Epub 2016 Jul 11. Nat Cell Biol. 2016. PMID: 27398910 Free PMC article.
Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response.
Sartorius R, D'Apice L, Trovato M, Cuccaro F, Costa V, De Leo MG, Marzullo VM, Biondo C, D'Auria S, De Matteis MA, Ciccodicola A, De Berardinis P. Sartorius R, et al. Among authors: de leo mg. EMBO Mol Med. 2015 Apr 17;7(7):973-88. doi: 10.15252/emmm.201404525. Print 2015 Jul. EMBO Mol Med. 2015. PMID: 25888235 Free PMC article.